| Primary Identifier | MGI:1913101 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 58187 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly; cell adhesion; and regulation of monoatomic ion transport. Predicted to act upstream of or within monoatomic ion transport. Located in bicellular tight junction; cytoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; lung; metanephros; olfactory epithelium; and submandibular gland primordium. Orthologous to human CLDN10 (claudin 10). PHENOTYPE: Mice lacking expression of this gene in the thick ascending limb of renal tubules display nephrocalcinosis, hypermagnesemia, and abnormalities in renal reabsorbtion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
