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Publication : Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

First Author  Mitsiadis TA Year  2001
Journal  Mech Dev Volume  109
Issue  2 Pages  399-403
PubMed ID  11731257 Mgi Jnum  J:73301
Mgi Id  MGI:2154859 Doi  10.1016/s0925-4773(01)00534-2
Citation  Mitsiadis TA, et al. (2001) Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression. Mech Dev 109(2):399-403
abstractText  The Notch signalling pathway defines a phylogenetically conserved cell-cell communication process that enables cell-fate specification in multicellular organisms. Deltex is a component of the Notch signalling network that physically interacts with the ankyrin repeats of Notch. Here, we report on the expression pattern of the Deltex1 gene during mouse embryonic development and, furthermore, we compare its expression with that of the Notch1, 2 and 3 genes. Complementary and combinatorial expression patterns between Deltex1 and the three Notch genes were observed throughout embryogenesis since Deltex1 expression was related either to cytodifferentiation (i.e. neuronal tissues) or to cell proliferation events (i.e. eye, vascular structures, hematopoiesis).
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