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Allele : Nr6a1<tm2Coo> nuclear receptor subfamily 6, group A, member 1; targeted mutation 2, Austin J Cooney

Primary Identifier  MGI:2448158 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nr6a1
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The 243 bp exon encoding the DNA-binding domain was replaced by a single loxP site after cre mediated recombination within ES cells. A truncated protein, lacking the DNA-binding domain but retaining the downstream ligand-binding domain was detected by Western blot analysis of homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • GCNF<lox>,
  • GCNF<lox>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele