| Type | MGI:General | Description | mice treated with doxycycline throughout gestation, birth, and rearing up to 6 weeks after birth exhibit an increase in myotonic dystrophy disease severity compared to mice treated with doxycycline starting at 2 months of age for a total of 8 weeks, showing a PR interval increase of 46.75% compared to 17.93% in the adult-induced mice, worse myotonia score, and more severe loss of grip strength, although a slightly milder muscle histology |
