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Protein Coding Gene : Rasal3 RAS protein activator like 3

Primary Identifier  MGI:2444128 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  320484
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of Ras protein signal transduction and positive regulation of NK T cell proliferation. Predicted to be located in cytoplasm and cytoplasmic side of membrane. Is expressed in thymus primordium. Orthologous to human RASAL3 (RAS protein activator like 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced NT T cells in the liver, increased granulocytes in the bone marrow and decreased susceptibility to alpha-GalCer-induced liver injury. [provided by MGI curators]
  • synonyms:
  • A430107D22Rik,
  • RAS protein activator like 3,
  • RIKEN cDNA A430107D22 gene,
  • Rasal3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For