Primary Identifier | MGI:1857167 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Alox5ap |
Transmission | Germline | Strain of Origin | DBA/1LacJ |
Is Recombinase | false | Is Wild Type | false |
description | Development of a DBA/1LacJ ES cell line enables gene targeting directly on the arthritis-susceptible background, as 129 ES cell lines generate mice that are not susceptible to collagen-induced arthritis (J:29897). |
molecularNote | A PGK-neomycin selection cassette was inserted into coding sequences of the gene. |