Primary Identifier | MGI:2672833 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bcl2l1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4 which encodes the carboxy terminal of the gamma isoform was replaced with a single loxP site after a floxed neomycin selection cassette was excised via cre mediated recombination. RT-PCR analysis of homozygous mutant T cells identified transcript encoding the L isoform in the absence of transcript encoding the gamma isoform. |