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Protein Coding Gene : Peli2 pellino 2
Primary Identifier  MGI:1891445 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  93834
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein-macromolecule adaptor activity. Predicted to be involved in protein polyubiquitination. Predicted to act upstream of or within positive regulation of MAPK cascade and positive regulation of protein phosphorylation. Located in cytosol and membrane. Is expressed in several structures, including neural tube; notochord; sensory organ; skeleton; and thymus. Orthologous to human PELI2 (pellino E3 ubiquitin protein ligase family member 2).
PHENOTYPE: Homozygous knockout reduces the immune response to gram-negative bacteria. [provided by MGI curators]
  • synonyms:
  • pellino 2,
  • BB129927,
  • MGI:2145853,
  • MGI:2145788,
  • expressed sequence AW047589,
  • AW047589,
  • Peli2,
  • expressed sequence BB129927
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

21 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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