| Primary Identifier | MGI:3040056 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 225471 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables phospholipid binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of interleukin-18-mediated signaling pathway; and response to interleukin-12. Acts upstream of or within defense response to virus and regulation of cytokine production. Located in endosome and plasma membrane. Is expressed in testis and ureter. Used to study Coronavirus infectious disease. Orthologous to human TICAM2 (TIR domain containing adaptor molecule 2). PHENOTYPE: Homozygous inactivation of this gene affects TLR4-mediated immune responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
