Primary Identifier | MGI:3718442 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | App |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A stop codon was introduced into exon 16 behind the alpha-secretase site at position QK612, flanked by a SV40 polyA site to ensure efficient polyadenylation of the mRNA. A floxed neo was removed via transient cre expression. |