| Primary Identifier | MGI:1346871 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 26400 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables magnesium ion binding activity; protein kinase activity; and protein phosphatase binding activity. Involved in several processes, including JNK cascade; cellular response to interleukin-1; and positive regulation of JNK cascade. Acts upstream of or within regulation of motor neuron apoptotic process and response to wounding. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; lung; musculoskeletal system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; lung carcinoma; and lung non-small cell carcinoma. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7). PHENOTYPE: Mice homozygous for disruptions in this gene die during embryogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
