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Allele : Tg(tetO-BRAF*V600E)29Lc transgene insertion 29, Lynda Chin

Primary Identifier  MGI:3834721 Allele Type  Transgenic
Attribute String  Constitutively active, Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO-BRAF*V600E)29Lc
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  The tetracycline operon was used to drive inducible expression of a human cDNA with nucleotide substitutions that result in the amino acid substitution of glutamic acid for valine at position 600 (V600E). This mutation creates a constitutively active form. Two lines were created (lines 29 and 13). Line 29 was selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • Tet-BRAF*,
  • Tet-BRAF*
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele