| Primary Identifier | MGI:104756 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 104099 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within neutrophil chemotaxis. Located in basal plasma membrane. Part of integrin alpha9-beta1 complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; skin; and vascular system. Used to study congenital chylothorax. Human ortholog(s) of this gene implicated in cerebral infarction; hypertension; and pancreatic cancer. Orthologous to human ITGA9 (integrin subunit alpha 9). PHENOTYPE: Homozygous mutation of this gene results in respiratory distress leading to postnatal lethality caused by an accumulation of pleural fluid rich in triglyceride, cholesterol and lymphocytes. Mice develop edema and lymphocytic infiltration in the chest wall. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
