Primary Identifier | MGI:7488139 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Ptgds |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A targeting vector was constructed with the nls-cre recombinase sequence fused to exon 1 of the Ptgds locus and a poly A signal with a floxed EGFP-hygromycin selection cassette 3' to the cre poly A signal. Homologous recombination in ES cells was performed to replace exon 1 with the targeting construct. |