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Protein Coding Gene : Pygo2 pygopus 2

Primary Identifier  MGI:1916161 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  68911
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity; histone acetyltransferase regulator activity; and histone binding activity. Acts upstream of or within several processes, including lens development in camera-type eye; regulation of mammary gland epithelial cell proliferation; and spermatid nucleus differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and skin. Orthologous to human PYGO2 (pygopus family PHD finger 2).
PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality, have small or absent lens, abnormal optic cup morphology, and impaired mammary gland epithelium proliferation. Mice homozygous for a knock-in allele exhibit normal development and fertility. [provided by MGI curators]
  • synonyms:
  • Pygo2,
  • 1190004M21Rik,
  • RIKEN cDNA 1190004M21 gene,
  • mpygo2,
  • pygopus 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For