| Type | MGI:General | Description | bone marrow-derived macrophages (BMDMs) show enhanced cell death when treated with necroptosis-inducing agents, including T/S/Z (a combination of TNF, a Smac mimetic, and a pan-caspase inhibitor Z-VAD-fmk), TRAIL/S/Z (TNF-related apoptosis-inducing ligand plus a Smac mimetic and z-VAD), or LPS/S/Z (LPS plus a Smac mimetic and z-VAD), relative to wild-type BMDMs primary testis cells isolated from the seminiferous tubules of 2-month old mice show significantly more cell death when treated with necroptosis stimuli T/S/Z than wild-type testis cells |
