Primary Identifier | MGI:3663254 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Clic5 |
Inheritance Mode | Recessive | Strain of Origin | C3H/HeJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 97 base pair deletion, including the 3'-most 87 base pairs of exon 5 and 10 base pairs of the flanking intron sequence including the exon/intron splice donor recognition sequence, results in a frame shift and premature stop codon in both Clic5A and Clic5B transcripts, effectively resulting in a null mutation of both transcripts. |