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Protein Coding Gene : Grpr gastrin releasing peptide receptor

Primary Identifier  MGI:95836 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  14829
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables neuropeptide receptor activity. Involved in several processes, including positive regulation of behavioral fear response; positive regulation of respiratory gaseous exchange; and psychomotor behavior. Acts upstream of or within regulation of cell population proliferation. Located in plasma membrane. Is expressed in dentate gyrus subgranular zone; lung; lung epithelium; lung mesenchyme; and small intestine epithelium. Orthologous to human GRPR (gastrin releasing peptide receptor).
PHENOTYPE: Male mice hemizygous for a knock-out allele lack bombesin-induced satiety response. Male mice hemizygous for another knock-out allele exhibit hyperactivity, abnormal social investigation, and insensitivity to gastrin-releasing peptide-induced hypothermia. [provided by MGI curators]
  • synonyms:
  • bombesin receptor,
  • gastrin releasing peptide receptor,
  • MGD-MRK-10276,
  • Grpr,
  • GRP-R

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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5 Driver For