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Protein Coding Gene : Mettl16 methyltransferase 16, N6-methyladenosine
Primary Identifier  MGI:1914743 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  67493
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables mRNA (N6-adenosine)-methyltransferase activity. Involved in mRNA catabolic process; mRNA destabilization; and mRNA methylation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system. Orthologous to human METTL16 (methyltransferase 16, RNA N6-adenosine).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality around implantation. [provided by MGI curators]
  • synonyms:
  • MGI:1924220,
  • A830095F14Rik,
  • methyltransferase 16, N6-methyladenosine,
  • Mettl16,
  • 2610100D03Rik,
  • expressed sequence AI846133,
  • RIKEN cDNA 2610100D03 gene,
  • RIKEN cDNA 2810013M15 gene,
  • MGI:2444613,
  • RIKEN cDNA A830095F14 gene,
  • methyltransferase 10 domain containing,
  • AI846133,
  • MGI:2144287,
  • Mett10d,
  • 2810013M15Rik
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