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Allele : Del(6Spam1-Hyal5)1Eki deletion, Chr 6, Ekyune Kim 1
Primary Identifier  MGI:7310454 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Del(6Spam1-Hyal5)1Eki
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology deleted a 56.9 kb genomic region encompassing Spam1 and Hyal5. Western blot analysis demonstrated absence of both proteins in cauda epididymal sperm. In addition, zymographic assays confirmed the complete absence of hyaluronidase activity in sperm.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • Spam1<->/Hyal5<->,
  • Spam1<->/Hyal5<->
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1 Feature

Trail: Allele

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0 Expresses

2 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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