| Primary Identifier | MGI:99611 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 13844 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables several functions, including amyloid-beta binding activity; identical protein binding activity; and transmembrane signaling receptor activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of intracellular signal transduction; and plasma membrane bounded cell projection organization. Acts upstream of or within several processes, including neuron projection morphogenesis; optic nerve morphogenesis; and regulation of neurogenesis. Located in several cellular components, including axon; dendrite; and neuronal cell body. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; neural ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in blood platelet disease. Orthologous to human EPHB2 (EPH receptor B2). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal axon guidance, circling, head bobbing, and hyperactivity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
