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Protein Coding Gene : Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3

Primary Identifier  MGI:1917171 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  229279
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA transmembrane transporter activity and mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splicing, via spliceosome and mRNA transport. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus and ribonucleoprotein granule. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in glutamatergic synapse and postsynaptic density. Is expressed in central nervous system and sensory organ. Orthologous to human HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality, lung developmental defects, reduced cortex thickness, and a mitotic delay in apical cortical progenitors resulting in impaired neurogenesis of early born deep-layer neurons. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2410013L13 gene,
  • RIKEN cDNA 2610209F03 gene,
  • MGI:2149675,
  • heterogeneous nuclear ribonucleoprotein A3,
  • RIKEN cDNA 2610510D13 gene,
  • Hnrnpa3,
  • Hnrpa3,
  • 2410013L13Rik,
  • 2610209F03Rik,
  • 2610510D13Rik,
  • MGI:2149671

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4 Involved In Mutations

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