| Primary Identifier | MGI:1927669 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 64385 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable arachidonic acid binding activity; heme binding activity; and monooxygenase activity. Predicted to be involved in leukotriene B4 catabolic process and omega-hydroxylase P450 pathway. Predicted to be located in apical plasma membrane; cytoplasm; and intracellular membrane-bounded organelle. Is expressed in liver; nervous system; and testis. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to several human genes including CYP4F2 (cytochrome P450 family 4 subfamily F member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced vitamin E-omega-hydroxylase activity and altered levels of tocopherols and their metabolites. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
