| Primary Identifier | MGI:4359649 | Allele Type | Chemically induced (ENU) |
| Gene | Themis | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | ENU mutagenesis caused a missense mutation in exon 4 of the gene where adenine was changed to a cystosine at position 1779 (A1779C). This resulted in a threonine-to-proline substitution at position 512 (T512P). Protein expression was significantly depressed in homozygote thymocytes compared to wild-type while mRNA levels were unaffected. |
