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Allele : Map2k6<tm1Flv> mitogen-activated protein kinase kinase 6; targeted mutation 1, Richard A Flavell

Primary Identifier  MGI:2673716 Allele Type  Targeted
Attribute String  Null/knockout Gene  Map2k6
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette inserted by homologous recombination replaced the exon encoding subdomain XI which is essential for catalytic activity. Protein was undetected by Western blot analaysis of splenocytes obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mkk6<->,
  • Mkk6<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele