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Protein Coding Gene : Treml1 triggering receptor expressed on myeloid cells-like 1

Primary Identifier  MGI:1918576 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  71326
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable transmembrane signaling receptor activity. Involved in platelet activation. Located in cell surface and platelet alpha granule. Is expressed in liver lobe and testis. Orthologous to human TREML1 (triggering receptor expressed on myeloid cells like 1).
PHENOTYPE: Mice homozygous for a knock-out allele show a reduced platelet count, defective platelet aggregation, prolonged bleeding times, enhanced inflammatory hemorrhage, and increased susceptibility to death from endotoxin (LPS) challenge. [provided by MGI curators]
  • synonyms:
  • 5430401J17Rik,
  • triggering receptor expressed on myeloid cells-like 1,
  • RIKEN cDNA 5430401J17 gene,
  • TLT-1,
  • Treml1

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For