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Allele : Blm<tm3Ches> Bloom syndrome, RecQ like helicase; targeted mutation 3, Nicholas Chester

Primary Identifier  MGI:2683764 Allele Type  Targeted
Attribute String  Null/knockout Gene  Blm
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed PGK-neomycin resistance gene was inserted into intron 8 and an additional loxP site was placed in intron 7, 75 bp from the start of exon 8. Both exon 8 and the neomycin gene were subsequently removed from correctly targeted ES cells by Cre-mediated recombination. A frame shift mutation is predicted at the splice site between exon 7 and exon 9 in the resulting transcript.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Blm-,
  • Blm-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele