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Comment :

Type  MGI:General Description  hypoglycemic response to exogenous IGF-1 is attenuated in transgenic animals relative to controls blood glucose levels in transgenic mice are higher at all time points after glucose challenge but difference is significant only at 60 and 120 minutes initial increase in blood glucose in response to IGF-1 observed in wild-type males is abolished in transgenic males glucocompetence deteriorates with age