Primary Identifier | MGI:2147611 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 68229 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in negative regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be active in nucleus and site of DNA damage. Orthologous to human SPINDOC (spindlin interactor and repressor of chromatin binding). PHENOTYPE: Mice homozygous for null mutations of this gene are viable but exhibit decreased body weight, reduced levels of PARylation, and increased sensitivity to ionizing radiation. [provided by MGI curators] |