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Protein Coding Gene : Spindoc spindlin interactor and repressor of chromatin binding

Primary Identifier  MGI:2147611 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  68229
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in negative regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be active in nucleus and site of DNA damage. Orthologous to human SPINDOC (spindlin interactor and repressor of chromatin binding).
PHENOTYPE: Mice homozygous for null mutations of this gene are viable but exhibit decreased body weight, reduced levels of PARylation, and increased sensitivity to ionizing radiation. [provided by MGI curators]
  • synonyms:
  • spindlin interactor and repressor of chromatin binding,
  • Spindoc,
  • AI846148,
  • expressed sequence AI846148

Features --> Cross References

Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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