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Protein Coding Gene : Thoc6 THO complex 6

Primary Identifier  MGI:2677480 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  386612
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA binding activity. Predicted to be involved in central nervous system development and mRNA export from nucleus. Predicted to act upstream of or within RNA processing; apoptotic process; and mRNA transport. Predicted to be located in nuclear speck. Predicted to be part of THO complex part of transcription export complex. Predicted to colocalize with chromosome, telomeric region. Orthologous to human THOC6 (THO complex subunit 6).
PHENOTYPE: Mice with biallelic loss of function are embryonic lethal by E11.5. Embryos are smaller, show developmental delay by E9.5, and show thinner epithelium in the telencephalic vesicles. [provided by MGI curators]
  • synonyms:
  • WD repeat domain 58,
  • RIKEN cDNA F830014G06 gene,
  • Wdr58,
  • Thoc6,
  • F830014G06Rik,
  • THO complex 6

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For