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Protein Domain : THO complex subunit 6

Primary Identifier  IPR042626 Type  Family
Short Name  THOC6
description  In humans, THOC6 is a component of the THO subcomplex of the TREX complex []. The THO complex is a conserved RNA binding complex that has been implicated in mRNA export of subsets of mRNAs.It plays an essential role in dopamine synaptogenesis []. Mutations in the THOC6 genes have been linked to intellectual disability []. In flies, THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress [].

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2 Protein Domain Regions