| Primary Identifier | MGI:87868 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 11409 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable butyryl-CoA dehydrogenase activity; identical protein binding activity; and nucleotide binding activity. Predicted to be involved in butyrate catabolic process and fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to act upstream of or within fatty acid metabolic process. Located in mitochondrion. Is expressed in several structures, including heart; liver; lung; pancreas; and placenta. Used to study short chain acyl-CoA dehydrogenase deficiency. Human ortholog(s) of this gene implicated in alcohol use disorder and short chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADS (acyl-CoA dehydrogenase short chain). PHENOTYPE: Mice homozygous for disruptions in this gene display organic aciduria and develop hypoglycemia and fatty livers after fasting. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
