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Protein Coding Gene : Ercc6l2 excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2

Primary Identifier  MGI:1923501 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  76251
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein kinase binding activity. Predicted to be involved in cellular response to reactive oxygen species and interstrand cross-link repair. Predicted to act upstream of or within DNA repair. Predicted to be located in mitochondrion and nucleus. Predicted to be part of protein-containing complex. Predicted to colocalize with centrosome. Orthologous to human ERCC6L2 (ERCC excision repair 6 like 2).
PHENOTYPE: Homozygous knockout affects DNA damage repair and results in reduced class switch recombination in B cells, reduced T cell numbers and reduced IgA and IgG serum levels. [provided by MGI curators]
  • synonyms:
  • 9330134C04Rik,
  • RIKEN cDNA 9330134C04 gene,
  • MGI:1916653,
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2,
  • 0610007P08Rik,
  • RIKEN cDNA 1700019D06 gene,
  • Ercc6l2,
  • MGI:3689365,
  • 1700019D06Rik,
  • RIKEN cDNA 0610007P08 gene

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