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Publication : New gene locus modifying susceptibility to certain B-tropic murine leukemia viruses.

First Author  Declève A Year  1976
Journal  Proc Natl Acad Sci U S A Volume  73
Issue  2 Pages  585-90
PubMed ID  174115 Mgi Jnum  J:5614
Mgi Id  MGI:54091 Doi  10.1073/pnas.73.2.585
Citation  Decleve A, et al. (1976) New gene locus modifying susceptibility to certain B-tropic murine leukemia viruses. Proc Natl Acad Sci U S A 73(2):585-90
abstractText  A new gene, SRV, the dominant allele of which occurs in mice of strain C57BL, independently modifies the slope (hitness) and level of sensitivity of the titration curves obtained when one subclass of B-tropic murine leukemia viruses is propagated on mouse embryo cells of nonpermissive Fv-1 genotypes. Replication of another subclass of B-tropic viruses is not modified with respect to hitness, and that of N-tropic viruses is not affected.
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