| Type | MGI:General | Description | at E15 and E16, heterozygous null skulls display a broader zone of mineralized trabeculae in the parietal bone relative to wild-type; osteocalcin is already detectable in the parietal bone and extends toward the midline at P2, mineralized trabeculae have reached the midline suture in heterozygous but not in wild-type skulls; osteocalcin is abnormally detectable on both sides of the suture and reaches the midline, indicating premature osteoblast differentiation |
