Primary Identifier | MGI:7485929 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Mafg-Nrf2/cre,-EGFP)737Hozu |
Strain of Origin | (C57BL/6 x DBA)F1 | Induced With | electrophilic stress |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgene consisting of the cDNA encoding Neh2 domain of the mouse Nrf2 gene (NRF2) fused to a Cre coding sequence followed by a CL1-PEST degradation signal was linked to the IRES-EGFP fragment and inserted downstream of the Mafg-regulatory domain (MGRD). Four founder progenies were obtained, and one of the transgenic mouse lines (line# 737) was selected and used for the studies. |