| Primary Identifier | MGI:3037070 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ighm |
| Transmission | Germline | Strain of Origin | BALB/cJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A single loxP site remained in place of a genomic fragment encompassing Igh-6 exons mu1 through mu4 and a portion of the intergenic region between Igh-6 and Igh-5 after the incorporation and subsequent excision of a floxed neo-HSV cassette. The intergenic region contained regulatory cis-elements of the Igh-5 locus. IgM (Igh-6) was undetected by flow cytometric analysis whereas levels of soluble IgD (Igh-5) were increased relative to wild-type. |
