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Publication : Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin.

First Author  Williams AF Year  1982
Journal  Science Volume  216
Issue  4547 Pages  696-703
PubMed ID  6177036 Mgi Jnum  J:32621
Mgi Id  MGI:80114 Doi  10.1126/science.6177036
Citation  Williams AF, et al. (1982) Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin. Science 216(4547):696-703
abstractText  The amino acid sequences of mouse brain Thy-1 glycoproteins are shown to be homologous to those of variable-region immunoglobulin domains. There is also good homology with constant domains and beta 2-microglobulin; overall the results suggest that Thy-1 may be like the primordial immunoglobulin domain. Preliminary evidence for an invertebrate Thy-1 homolog supports this possibility.
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