| Primary Identifier | MGI:1858212 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 53867 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables heparin binding activity. Acts upstream of or within cell-matrix adhesion. Located in collagen-containing extracellular matrix. Part of collagen type V trimer. Is expressed in several structures, including bone; embryo mesenchyme; extraembryonic component; placenta; and tongue. Orthologous to human COL5A3 (collagen type V alpha 3 chain). PHENOTYPE: Mice homozygous for a null mutation show decreased pancreatic beta cell mass, hyperglycemia, hypoinsulinemia, impaired glucose tolerance, insulin resistance and impaired glucose uptake. Homozygous females show decreased susceptibility to diet-induced obesity and a thin hypodermal fat layer. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
