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Protein Coding Gene : Nudt1 nudix hydrolase 1

Primary Identifier  MGI:109280 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  17766
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity and snoRNA binding activity. Predicted to be involved in DNA protection and purine nucleoside catabolic process. Predicted to be located in several cellular components, including acrosomal vesicle; mitochondrial matrix; and nuclear membrane. Predicted to be active in cytoplasm. Orthologous to human NUDT1 (nudix hydrolase 1).
PHENOTYPE: Aging mice homozygous for a knock-out allele show increased incidence of tumor formation in the lung, liver and stomach. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-38325,
  • Mth1,
  • mutT, 8-oxo-dGTPase (E. coli),
  • nudix (nucleoside diphosphate linked moiety X)-type motif 1,
  • nudix hydrolase 1,
  • mutT, 8-oxo-dGTPase (E.coli),
  • 8-oxo-7,8-dihydro-2'-dGTPase,
  • Nudt1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For