Primary Identifier | IPR021818 | Type | Domain |
Short Name | SIPA1L_C |
description | This domain is found in C-terminal of the signal-induced proliferation-associated 1-like (SIPA1L) proteins, including SIPA1L 1-3 from humans. SIPA1Ls shares protein sequence similarity with signal-induced proliferation-associated protein 1 (SIPA1), which is a GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 [, ]. In rats SIPA1L1 (also known as SPAR) has been identified as a Rap-specific GTPase-activating protein []. |