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Protein Coding Gene : Top1 topoisomerase (DNA) I
Primary Identifier  MGI:98788 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  21969
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Acts upstream of or within DNA replication; DNA topological change; and embryonic cleavage. Located in cytoplasm; male germ cell nucleus; and perikaryon. Is expressed in brain; cerebral cortex subventricular zone; cerebral cortex ventricular layer; cortical plate; and telencephalon. Orthologous to human TOP1 (DNA topoisomerase I).
  • synonyms:
  • AI467334,
  • expressed sequence AI467334,
  • MGD-MRK-15167,
  • RIKEN cDNA D130064I21 gene,
  • Top1,
  • MGI:2138977,
  • topoisomerase (DNA) I,
  • MGD-MRK-15165,
  • D130064I21Rik,
  • Top-1
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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