Primary Identifier | MGI:3652045 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 622480 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in piRNA-mediated retrotransposon silencing by heterochromatin formation and spermatogenesis. Located in nucleus. Orthologous to human SPOCD1 (SPOC domain containing 1). PHENOTYPE: Homozygous knockout affects DNA methylation of transposable elements, leading to male sterility. [provided by MGI curators] |