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Protein Coding Gene : Nck1 non-catalytic region of tyrosine kinase adaptor protein 1

Primary Identifier  MGI:109601 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  17973
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ephrin receptor binding activity; eukaryotic initiation factor eIF2 binding activity; and protein domain specific binding activity. Involved in regulation of gene expression and regulation of response to endoplasmic reticulum stress. Acts upstream of or within several processes, including ephrin receptor signaling pathway; plasma membrane bounded cell projection assembly; and positive regulation of cellular component organization. Located in cell-cell junction and vesicle membrane. Is expressed in several structures, including extraembryonic component; hemolymphoid system gland; male reproductive gland or organ; nervous system; and somite. Orthologous to human NCK1 (NCK adaptor protein 1).
PHENOTYPE: Mice homozygous for disruption of this gene display no abnormal phenotype. [provided by MGI curators]
  • synonyms:
  • Nck1,
  • RIKEN cDNA D230010O13 gene,
  • MGD-MRK-39600,
  • Nck,
  • D230010O13Rik,
  • RIKEN cDNA 6330586M15 gene,
  • 6330586M15Rik,
  • MGI:2441955,
  • MGI:2441714,
  • non-catalytic region of tyrosine kinase adaptor protein 1,
  • non-catalytic region of tyrosine kinase,
  • MGI:1097154

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

33 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For