| First Author | Yamaoka T | Year | 1995 |
| Journal | Genomics | Volume | 27 |
| Issue | 2 | Pages | 337-40 |
| PubMed ID | 7558001 | Mgi Jnum | J:26190 |
| Mgi Id | MGI:73855 | Doi | 10.1006/geno.1995.1051 |
| Citation | Yamaoka T, et al. (1995) Cloning and mapping of the U2af1-rs2 gene with a high transmission distortion in interspecific backcross progeny. Genomics 27(2):337-40 |
| abstractText | We have cloned and analyzed the mouse U2af1-rs2 gene based on its sequence similarity to the imprinted gene U2af1-rs1 (SP2). Sequence analysis of this U2af1-rs2 cDNA revealed that it contained an open reading frame encoding a protein of 462 amino acid residues. The predicted amino acid sequence showed 72.7 and 35.8% identity to the U2af1-rs1 and U2 small nuclear ribonucleoprotein auxiliary factor, respectively. Interspecific backcross analysis showed this gene to map to the distal region of the X chromosome and also indicated that there was significant distortion of transmission ratio of the U2af1-rs2 allele in the backcrossed progeny from (C57BL/6J x Mus spretus)F1 females mated to Mus spretus males. |
