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Protein Coding Gene : Eya2 EYA transcriptional coactivator and phosphatase 2

Primary Identifier  MGI:109341 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  14049
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables protein tyrosine phosphatase activity. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand; mitochondrial outer membrane permeabilization; and striated muscle tissue development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; nervous system; non-neural ectoderm; and sensory organ. Orthologous to human EYA2 (EYA transcriptional coactivator and phosphatase 2).
PHENOTYPE: Mice homozygous for a null allele exhibit mild hearing loss and small thymus. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI327163,
  • MGI:2138916,
  • MGD-MRK-38386,
  • AI327163,
  • EYA transcriptional coactivator and phosphatase 2,
  • Eya2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For