| First Author | Sasahara K | Year | 2000 |
| Journal | Biochem Biophys Res Commun | Volume | 269 |
| Issue | 2 | Pages | 444-50 |
| PubMed ID | 10708573 | Mgi Jnum | J:61074 |
| Mgi Id | MGI:1354414 | Doi | 10.1006/bbrc.2000.2301 |
| Citation | Sasahara K, et al. (2000) Molecular cloning and expression analysis of a putative nuclear protein, SR-25. Biochem Biophys Res Commun 269(2):444-50 |
| abstractText | We cloned a full-length mouse cDNA and its human homologue encoding a novel protein designated as 'SR-25.' In Northern blot analysis, SR-25 mRNA was expressed in all organs tested, and relatively abundant in testis and thymus. Deduced amino acid sequences of mouse SR-25 and human SR-25 showed 77.7% identity. SR-25 has a serine-arginine repeat (SR repeat) and two types of amino acid clusters: a serine cluster and a highly basic cluster. Based on the presence of many nuclear localizing signals and a similarity to RNA splicing proteins, SR-25 is strongly suggested to be a nuclear protein and may contribute to RNA splicing. Copyright 2000 Academic Press. |
