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HT Experiment :

Experiment Id  E-MTAB-2742 Name  Expression profiling of ncRNAs with custom microarray of CaV 1.3 knockout mice compared to wild type mice
Experiment Type  transcription profiling by array Study Type  WT vs. Mutant
Source  ArrayExpress Curation Date  2019-05-31
description  For screening mouse models for CNS diseases for changes in ncRNA expression, we first investigated two models with impaired voltage-gated Ca2+ channel activity, i.e. the lethargic mutant of the auxiliary calcium channel beta4 subunit (Cacnb4lh; (Burgess et al. 1997)) and knockout mice for the L-type calcium channel CaV1.3 (Platzer et al. 2000), which have been implicated in a variety of neurological disorders such as psychiatric disorders (Cacnb4) or Parkinsons disease (Cav1.3).
  • variables:
  • genotype

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment