| Primary Identifier | MGI:2135508 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pdgfrb |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette replaced 1.8 kb of genomic sequence, which encodes part of the signal peptide and the second immunoglobulin domain. Northern blot analysis detected a shorter transcript in homozygous mutant mice that was presumed to be due to exon skipping. Western blot analysis of total protein failed to detect any encoded protein in homozygous mice. |
