| Primary Identifier | MGI:2449455 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 380713 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable low-density lipoprotein particle binding activity and scavenger receptor activity. Involved in neuron remodeling and positive regulation of axon regeneration. Acts upstream of or within dendrite development. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in brain; dorsal root ganglion; early conceptus; and spinal cord. Orthologous to human SCARF1 (scavenger receptor class F member 1). PHENOTYPE: Homozygous null mice are viable and fertile with no abnormalities detected in plasma glucose, cholesterol, or triglycerides, or in the brain, lung, heart, kidney, liver, or testes. Mice homozygous for a targeted allele exhibit impaired clearance of apoptotic cells and autoimmune disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
